Human platelet nitric oxide synthase activity: an optimized method

Nitric oxide and nitric oxide synthase activity in plants.

Research on NO in plants has gained considerable attention in recent years mainly due to its function in plant growth and development and as a key signalling molecule in different intracellular processes in plants. The NO emission from plants is known since the 1970s, and now there is abundant information on the multiple effects of exogenously applied NO on different physiological and biochemic...

Human seminal plasma inhibits brain nitric oxide synthase activity.

Nitric oxide is a chemical messenger which functions as a neurotransmitter or as a cytotoxic agent. Nitric oxide synthase (NOS) has been isolated from various mammalian reproductive tissues. The presence or absence of NOS in spermatozoa has not yet been reported. We therefore tested human and murine spermatozoa for NOS activity by measuring the conversion of arginine to citrulline. No activity ...

Nitric oxide synthase activity in human gynecological cancer.

Nitric oxide is generated by the NO synthases, a family of isoenzymes expressed in a wide range of mammalian cells. In the vascular and nervous systems distinct isoforms generate NO to act as a signal transduction mechanism. The isoform induced by cytokines, on the other hand, provides a sustained release of NO which mediates some cytotoxic and cytostatic effects of the immune system. Solid tum...

Nitric Oxide Synthase Activity and Tumor Progression

1 The Role of Nitric Oxide Synthase Uncoupling in Tumor Progression Christopher S. Rabender, Asim Alam, Gobalakrishnan Sundaresan, Robert J. Cardnell, Vasily A. Yakovlev, Nitai D. Mukhopadhyay, Paul Graves, Jamal Zweit, Ross B. Mikkelsen Department of Radiation Oncology, Department of Radiology and Center for Molecular Imaging, Department of Biostatistics, Virginia Commonwealth University, Rich...

Tetrahydrobiopterin and endothelial nitric oxide synthase activity.